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Pre-Registration Exam Practice Questions

BNF Exercise Section 1

Central Nervous System Part 1

Closed Book

1)   Which of the following is NOT a side effect of benzodiazepines:

A.   Decrease in responsiveness

B.    Antisocial behaviour

C.   Aggression

D.   Excitement

E.    Convulsions

 

2) Use of chlormethiazole in alcohol withdrawal should NOT be longer than

A.   5 days

B.    6 days

C.   7 days

D.   8 days

E.    9 days

 

3) Which of the following is not an example of extra-pyramidal side effects: 

A.   Tardive Dyskinesia

B.    Locomotor Ataxia

C.   Parkinsonian tremor

D.   Dystonia

E.    Akathisia

 

4.  Which of the following anti-psychotic can be used to treat violent patients without causing stupor? Agitated states in the elderly can also be control with the drug in the dose of 10 mg to 25mg with little risk of inducing confusion.

A.   Loxapine

B.    Promazine

C.   Thioridazine

D.   Chlorpromazine

E.    Sulpiride

 

5.  Which of the following is not a possible side effect of clozapine?

A.   Prostatic hypertrophy

B.    Constipation

C.   Agranulocytosis

D.   Arrhythmias

E.    Temperature deregulation

 

6.  Lithium dose is adjusted according to which of the following plasma concentration

A.   0.3 to 0.6mmol/l

B.    0.4 to 1.3mmol/l

C.   0.4 to 1mmol/l

D.   0.5 to 1.3mmol/l

E.    0.6 to 1.4mmol/l

 

Directions Summarised

A

1,2,3

B

1,2 only

C

2,3 only

D

1 only

E

3 only

 

7) Use of diazepam is contra-indicated or cautioned in which of the following conditions:

1.    Myasthenia gravis

2.    Acute respiratory distress

3.    Liver cirrhosis

 

8) Abrupt withdrawal of benzodiazepines can cause which of following:

1.    Psychosis

2.    Delirium

3.    Confusion

 

9) Which of the following statements regarding benzodiazepines is incorrect 

1.    Withdrawal symptoms can occur anytime up to 3 weeks after stopping a long acting benzodiazepine

2.    Withdrawal syndrome can occur within one or 2 hours after stopping a short acting benzodiazepine

3.    Rebound drowsiness can be one of the symptoms of withdrawal

 

10) Which of the following statements regarding clomethiazole is correct: 

1.    It has a long duration of action

2.    Use in alcohol withdrawal is undesirable

3.    It is a useful hypnotic in the elderly as it has little hangover effects

 

Directions Summarised

A

1,2,3

B

1,2 only

C

2,3 only

D

1 only

E

3 only

 

11) Use of antipsychotics is contra-indicated in which of the following: 

1.    Comatose state

2.    CNS depression

3.    Phaeochromocytoma (Vascular tumour of adrenal medulla)

 

12) Which of the following is a licensed indication of lithium

1.    Treatment of newly diagnosed depression

2.    Treatment of bipolar disorder

3.    Prophylaxis of bipolar disorder

 

13) Long term use of lithium is associated with

1.    Memory loss

2.    Cognitive impairment

3.    Thyroid dysfunction

 

Directions Summarised

 

First

Statement

Second Statement

 

A

True

True

2nd statement is a correct explanation of the first statement

B

True

True

2nd statement is NOT a correct explanation of the first

C

True

False

 

D

False

True

E

False

False

 

14)

Statement one:

Use of anxiolytics should be avoided during bereavement

Statement two:

Psychological adjustment during bereavement may be inhibited by the use of anxiolytics

  


Directions Summarised

 

First

Statement

Second Statement

 

A

True

True

2nd statement is a correct explanation of the first statement

B

True

True

2nd statement is NOT a correct explanation of the first

C

True

False

 

D

False

True

E

False

False

15)

Statement one:

Lorazepam and oxazepam are preferred benzodiazepines in hepatic impairment

Statement two:

Lorazepam and oxazepam carry a lower risk of withdrawal symptoms

 

16)

Statement one: 

Beta-blockers have an effect on psychological symptoms, such as worry, tension and fear

Statement two:

Beta-blockers can reduce autonomic symptoms such as palpitations and tremor.

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We are now working hard to update the site. We are slowly uploading more past exam questions with extended answers. Good luck to all the new pre-reg students.

 

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